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Clinically malignant atypical glomus tumour.
Fariba Binesh1, Ali Akhavan, Shokouh Taghipour Zahir
1Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. binesh44@yahoo.com
BMJ Case Reports
|January 8, 2013
Summary
Metastasizing glomus tumors (GTs) are rare. This case highlights a glomus tumor of uncertain malignant potential that recurred and metastasized to the lungs, necessitating chemotherapy.
Area of Science:
- Oncology
- Pathology
Background:
- Glomus tumors (GTs) typically present as small, benign neoplasms in the skin or subcutaneous tissue.
- Atypical or malignant variants of glomus tumors are infrequently reported.
Observation:
- A 2 cm subcutaneous nodule in the right scapular area was identified in a male patient.
- Microscopic examination revealed glomus tumor features with increased mitotic activity, suggesting uncertain malignant potential.
Findings:
- The patient experienced recurrence of the glomus tumor three months post-excision.
- Metastatic disease was confirmed with bilateral pulmonary involvement during metastasis work-up.
Implications:
- This case underscores the rare but significant potential for metastasis in glomus tumors, even those initially classified as having uncertain malignant potential.
- Aggressive management, including chemotherapy, may be required for metastasizing glomus tumors.