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Rett syndrome: a longitudinal developmental case report.

N Garber¹, N Veydt

¹Ohio University, School of Hearing and Speech Sciences, Athens 45701.

Journal of Communication Disorders

|February 1, 1990

Summary

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Rett syndrome causes developmental stagnation and regression in females, particularly impacting cognitive and communication skills. Gross motor and self-help skills showed relative strength despite intensive interventions.

Area of Science:

Neurology
Developmental Pediatrics

Background:

Rett syndrome is a progressive neurological disorder affecting only females.
Characterized by severe intellectual disability, loss of hand use, and repetitive movements.

Observation:

The study assessed development across gross motor, fine motor, self-help, communication, and cognitive domains.
Developmental stagnation was observed around 15 months of age.

Findings:

No skills advanced beyond a 2-year level, even with intensive interdisciplinary intervention.
Cognitive and communication skills showed initial regression, stabilization, and subsequent further decline.
Gross motor and self-help skills represented areas of relative developmental strength.

Implications:

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Highlights the severe, progressive nature of Rett syndrome and limited efficacy of current interventions.
Suggests a need for targeted therapies focusing on gross motor and self-help skills.
Underscores the profound impact on cognitive and communication abilities in affected individuals.