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Published on: August 19, 2025
Robot-assisted hysterectomy compared to open and laparoscopic approaches: systematic review and meta-analysis
Michelle O'Neill1, Patrick S Moran, Conor Teljeur
1Health Technology Assessment, Health Information and Quality Authority, George's Court, George's Lane, Dublin 7, Ireland. moneill@hiqa.ie
Purpose:
To review the safety and effectiveness of robot-assisted hysterectomy compared to traditional open and conventional laparoscopic surgery, differentiating radical, simple total with node staging, and simple total hysterectomy.
Methods:
Medline, Embase, the Cochrane library, and the Journal of Robotic Surgery were searched for controlled trials and observational studies with historic or concurrent controls. Data were pooled using random effects meta-analysis.
Results:
Compared to open surgery, robot-assisted radical hysterectomy is associated with reduced hospital stay and blood transfusions. For simple total hysterectomy with node staging, robot-assisted surgery is associated with reduced hospital stay, complications, and blood transfusions compared to open surgery. Compared to conventional laparoscopic surgery, robot-assisted simple total hysterectomy with node staging is associated with complications and conversions.
Conclusions:
Compared to open surgery, robot-assisted hysterectomy offers benefits for reduced length of hospital stay and blood transfusions. The best evidence of improved outcomes is for simple total hysterectomy with node staging. Study quality was poor.

