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Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
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Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and acquisition...
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Staphylococcal Skin Infections

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Updated: May 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Methicillin-resistant Staphylococcus aureus in obstetrics.

Jeanne S Sheffield1

  • 1Division, Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. jeanne.sheffield@utsouthwestern.edu

American Journal of Perinatology
|January 8, 2013
PubMed
Summary
This summary is machine-generated.

Methicillin-resistant Staphylococcus aureus (MRSA) is a growing threat in obstetrics, causing various infections. This review covers MRSA

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Obstetrics

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) is a significant multidrug-resistant pathogen.
  • MRSA infections are increasingly prevalent in the obstetric population, leading to complications like mastitis and wound infections.

Purpose of the Study:

  • To provide a comprehensive review of MRSA in obstetrics.
  • To discuss epidemiology, pathogenesis, clinical presentations, and management strategies for MRSA in obstetric patients.

Main Methods:

  • Literature review focusing on MRSA in obstetrics.
  • Analysis of current treatment guidelines (2011 IDSA).
  • Discussion of prevention and decolonization strategies.

Main Results:

  • MRSA is associated with diverse obstetric infections, including skin/soft tissue, mastitis, and wound infections.
  • Current guidelines offer management options for invasive and noninvasive MRSA.
  • Decolonization is a key prevention strategy.

Conclusions:

  • Effective management and prevention of MRSA in obstetrics are crucial.
  • Adherence to treatment guidelines and implementation of decolonization protocols are recommended.
  • Continued vigilance against MRSA in obstetric care is necessary.