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Updated: May 15, 2026

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
Published on: January 22, 2020
Vaccination issues in patients with inflammatory bowel disease receiving immunosuppression
1Dr. Dezfoli is a PGY-3 Resident in Internal Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Melmed is the Director of Clinical Trials at the Inflammatory Bowel Disease Center at Cedars-Sinai Medical Center and an Assistant Clinical Professor of Medicine at the David Geffen School of Medicine at the University of California, Los Angeles, both in Los Angeles, California.
Abstract:
Treatment regimens for Crohn's disease and ulcerative colitis increase susceptibility to infections, many of which can be prevented by vaccinations. Increased awareness concerning vaccine-preventable diseases has led to several studies investigating the immunologic responses to vaccines in immunosuppressed patients with inflammatory bowel disease. This review provides an overview of the evidence-based rationale for currently accepted recommendations regarding the use of both inactivated and live vaccines in this unique population.
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