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Updated: Feb 1, 2026
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Biology of Microbial Communities - Interview
Published on: May 27, 2007
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A conversation with Paul Greengard. Interview by Eric J Nestler
Annual Review of Pharmacology and Toxicology
|January 9, 2013
Summary
Nobel laureate Paul Greengard
Area of Science:
- Neuroscience
- Molecular Biology
- Biophysics
Background:
- Paul Greengard's early career included service in the US Navy and doctoral studies in biophysics.
- He held positions at Geigy, Albert Einstein College of Medicine, and Vanderbilt University before joining Yale University.
Discussion:
- Greengard's research at Yale demonstrated the role of cyclic nucleotides, protein kinases, and phosphatases in regulating synaptic transmission.
- His work at The Rockefeller University has advanced understanding of brain disorders like schizophrenia, Alzheimer's, and Parkinson's disease.
Key Insights:
- Demonstrated the critical role of intracellular signaling molecules in neuronal function.
- Elucidated molecular mechanisms underlying synaptic plasticity and neurotransmission.
Outlook:
- Greengard's research provides a foundation for developing novel therapeutic strategies for neurological and psychiatric conditions.
- His work continues to influence the field of neuroscience and brain disorder research.
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