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Updated: May 15, 2026

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
08:34

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion

Published on: February 24, 2021

The use of platelet-rich plasma in plastic surgery remains unproven

M Felix Freshwater1

  • 1Florida International University College of Medicine, 9155 S Dadeland Blvd., Suite 1404, Miami, FL 33156-2739, USA. mfelix.freshwater@gmail.com

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
|January 9, 2013
PubMed
Abstract

No abstract available in PubMed .

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The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...