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Intradermal Microdialysis: An Approach to Investigating Novel Mechanisms of Microvascular Dysfunction in Humans

Intradermal Microdialysis: An Approach to Investigating Novel Mechanisms of Microvascular Dysfunction in Humans

Published on: July 21, 2023

Adding a life-course perspective to cardiovascular-risk communication.

Kunal N Karmali¹, Donald M Lloyd-Jones

¹Department of Medicine-Cardiology, Northwestern University Feinberg School of Medicine, 676 North St Clair Street, Suite 600, Chicago, IL 60611, USA.

Nature Reviews. Cardiology

|January 9, 2013

Summary

Current cardiovascular disease (CVD) prevention focuses on short-term risk. Estimating lifetime risk and using tools like risk-adjusted age can improve patient understanding and motivate early intervention for better cardiovascular health.

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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

Area of Science:

Cardiology
Preventive Medicine
Public Health

Background:

Current cardiovascular disease (CVD) primary prevention relies on short-term (5-10 year) risk estimation.
This approach may overlook individuals with existing atherosclerosis who could benefit from earlier intervention.
Physician-patient conversations about CVD risk often focus on immediate threats.

Approach:

Proposes using lifetime CVD risk estimation as an adjunct to traditional 10-year risk assessments.
Introduces novel risk communication methods, including risk-adjusted age.
Advocates for integrating these strategies into routine clinical practice.

Key Points:

Lifetime risk assessment can identify a broader population for preventive therapies.
Risk-adjusted age offers a novel way to communicate individual CVD risk.
Enhanced risk communication can improve patient engagement and adherence to preventive measures.

Conclusions:

Shifting focus to lifetime risk and novel communication tools can optimize CVD prevention.
These strategies aim to motivate earlier lifestyle changes and therapy adherence.
Improved understanding of long-term risk may lead to more effective CVD management.