Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glassware Calibration

Glassware Calibration

Accurate calibration of glassware, such as volumetric flasks, pipettes, and burettes, is essential to ensure accurate measurements in the analytical laboratory. Calibration helps maintain consistency across measurements and prevents errors arising from inaccurate volumes.
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Changes in bone marrow fat fraction and immune cell counts in women with cervical cancer treated with primary chemoradiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2025

Same author

Intra-prostatic recurrences after radiotherapy with focal boost: Location and dose mapping in the FLAME trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology·2024

Same author

Future of Multidisciplinary Team in the Context of Adaptive Therapy.

Seminars in radiation oncology·2024

Same author

A DWI-based hypoxia model shows robustness in an external prostatectomy cohort.

Frontiers in oncology·2024

Same author

Validation of quantitative magnetic resonance imaging techniques in head and neck healthy structures involved in the salivary and swallowing function: Accuracy and repeatability.

Physics and imaging in radiation oncology·2024

Same author

Deep learning based MLC aperture and monitor unit prediction as a warm start for breast VMAT optimisation.

Physics in medicine and biology·2023

Search research articles

Related Experiment Video

Updated: May 15, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

Calibrating page sized Gafchromic EBT3 films.

W Crijns¹, F Maes, U A van der Heide

¹Department of Radiation Oncology, University Hospitals Leuven, Leuven, Belgium. wouter.crijns@uzleuven.be

Medical Physics

|January 10, 2013

Summary

A new calibration method for Gafchromic EBT3 films accurately measures radiation doses for complex radiotherapy treatments. This approach uses only two films and corrects for lateral scan effects, ensuring precise dosimetry with minimal errors.

More Related Videos

Electrospray Deposition of Uniform Thickness Ge23Sb7S70 and As40S60 Chalcogenide Glass Films

Electrospray Deposition of Uniform Thickness Ge₂₃Sb₇S₇₀ and As₄₀S₆₀ Chalcogenide Glass Films

Published on: August 19, 2016

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Related Experiment Videos

Last Updated: May 15, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

Electrospray Deposition of Uniform Thickness Ge23Sb7S70 and As40S60 Chalcogenide Glass Films

Electrospray Deposition of Uniform Thickness Ge₂₃Sb₇S₇₀ and As₄₀S₆₀ Chalcogenide Glass Films

Published on: August 19, 2016

Bridging the Bio-Electronic Interface with Biofabrication

Bridging the Bio-Electronic Interface with Biofabrication

Published on: June 6, 2012

Area of Science:

Medical Physics
Radiation Oncology
Radiotherapy Dosimetry

Background:

Gafchromic EBT3 films are widely used for radiation dosimetry.
Accurate dose verification is crucial for Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT).
Lateral scan effects can introduce errors in large-area film dosimetry.

Purpose of the Study:

To develop a novel calibration method for Gafchromic EBT3 films for dosimetry.
To enable pretreatment verification of VMAT and IMRT with large exposed film areas.
To account for and correct lateral scan errors using calibration data itself.

Main Methods:

Modeled film measurements using relative scan values (Transmittance, T).
Developed a linear combination model for transmittance states and a parabolic lateral scan correction.
Used a rational calibration function to link transmittance to dose.
Compared four calibration setups (varying number of ROIs and films) for dose estimation accuracy.
Validated the method using film strips with known doses over a week.

Main Results:

A two-film calibration provided optimal cost-effectiveness and dosimetric accuracy.
Validation showed dose errors of 1%-2% (max 0.05 Gy) at two time points.
Lateral scan correction effectively minimized RMSE differences across the film.
The method achieved residual dose errors ≤2% or ≤0.05 Gy.

Conclusions:

EBT3 Gafchromic films can be calibrated for large-field dosimetry using minimal films and static fields.
A linear combination of transmittance states and a rational function accurately model dose.
Lateral scan effects are resolved within the calibration function.
The developed method allows for accurate dosimetry with only two calibration films.