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Updated: May 15, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
Published on: July 1, 2014
Attentional functioning in patients with posttraumatic stress disorder: a preliminary study
Michael David Horner1, Jacobo E Mintzer, Travis H Turner
1Ralph H. Johnson Department of Veterans Affairs Medical Center, Charleston, SC, USA. hornermd@musc.edu
Objective:
To compare patients with posttraumatic stress disorder (PTSD) to patients without psychiatric or cognitive disorders on neuropsychological measures of attention.
Methods:
The sample included 19 patients with PTSD and 22 participants with no cognitive or psychiatric diagnosis. All had been referred for clinical neuropsychological evaluation at a VA Medical Center. None were diagnosed with dementia, delirium, or current substance dependence except nicotine or caffeine, and none had a history of stroke or of traumatic brain injury with loss of consciousness. Patients were excluded if they failed to exert adequate effort on testing.
Results:
PTSD patients performed significantly more poorly than patients without psychiatric diagnoses on Digit Span.
Conclusion:
PTSD patients were impaired relative to participants without psychiatric diagnoses on a measure of focused attention. Several factors, including the small sample size, suggest that the results should be considered preliminary.
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