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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Pulmonary Edema II: Pathophysiology01:18

Pulmonary Edema II: Pathophysiology

Pulmonary edema is the accumulation of fluid in the interstitial and alveolar spaces of the lungs, impairing gas exchange and oxygen delivery. It may be cardiogenic or noncardiogenic, but both reduce oxygenation and lung compliance.Cardiogenic Pulmonary EdemaCardiogenic edema results from increased hydrostatic pressure in pulmonary capillaries, usually due to left ventricular dysfunction from myocardial infarction, heart failure, or valvular disease. Ineffective cardiac pumping causes blood to...

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Related Experiment Video

Updated: May 15, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Submassive pulmonary embolism.

Gregory Piazza1

  • 1Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115, USA. gpiazza@partners.org

JAMA
|January 10, 2013
PubMed
Summary
This summary is machine-generated.

Acute pulmonary embolism (PE) poses a significant mortality risk. Identifying high-risk patients and determining optimal treatment, including advanced interventions and long-term management, is crucial for improving outcomes in acute PE cases.

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Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
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Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

Related Experiment Videos

Last Updated: May 15, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
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A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
08:02

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

Area of Science:

  • Cardiology
  • Pulmonology
  • Emergency Medicine

Background:

  • Acute pulmonary embolism (PE) is a leading cause of preventable death in the US.
  • Estimates suggest 100,000 to 180,000 annual deaths from PE.
  • Submassive PE with right ventricular dysfunction presents a complex clinical challenge.

Observation:

  • Risk stratification for acute PE involves clinical examination, ECG, cardiac biomarkers, CT scans, and echocardiography.
  • Identifying high-risk patients is key to determining the need for aggressive therapy beyond anticoagulation.
  • Ms. A's case highlights the diagnostic and therapeutic dilemmas in managing submassive PE.

Findings:

  • Advanced treatment options for high-risk acute PE include systemic fibrinolysis, catheter-directed therapy, and surgical embolectomy.
  • Inferior vena cava filters are also an intervention option for select patients.
  • Diagnostic tools aid in assessing the severity and guiding treatment decisions.

Implications:

  • Optimal anticoagulation duration and lifestyle modifications are essential for long-term cardiovascular risk reduction.
  • Timely and accurate risk stratification can lead to more effective and potentially life-saving interventions.
  • Further research into risk stratification and treatment protocols for acute PE is warranted.