Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
  1. Home
  3. Narrow Band Imaging To Differentiate Neoplastic And Non-neoplastic Colorectal Polyps In Real Time: A Meta-analysis Of Diagnostic Operating Characteristics.
  1. Home
  3. Narrow Band Imaging To Differentiate Neoplastic And Non-neoplastic Colorectal Polyps In Real Time: A Meta-analysis Of Diagnostic Operating Characteristics.

Related Experiment Video

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Narrow band imaging to differentiate neoplastic and non-neoplastic colorectal polyps in real time: a meta-analysis of

Sarah K McGill1, Evangelos Evangelou, John P A Ioannidis

  • 1Gastroenterology Section, Veterans Affairs Palo Alto, and Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.

Gut
|January 10, 2013

View abstract on PubMed

Summary
This summary is machine-generated.
Keywords:
Colonic PolypsColonoscopyColorectal Cancer ScreeningColorectal NeoplasiaMeta-Analysis

More Related Videos

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

Related Experiment Videos

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
10:35

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis

Published on: October 17, 2016

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

Narrow band imaging (NBI) colonoscopy accurately differentiates colorectal polyps, showing high sensitivity and specificity. This advanced imaging technique has significant potential for real-time endoscopic diagnosis, potentially replacing pathological analysis for diminutive polyps.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Diagnostic Imaging

Background:

  • Narrow band imaging (NBI) colonoscopy is increasingly used to distinguish neoplastic from non-neoplastic colorectal polyps.
  • NBI has demonstrated potential to replace pathological diagnosis for diminutive polyps.

Purpose of the Study:

  • To conduct a systematic review and meta-analysis of the real-time diagnostic performance of NBI colonoscopy for colorectal polyps.
  • To evaluate the accuracy of NBI in differentiating polyp types during colonoscopy.

Main Methods:

  • Systematic search of PubMed, SCOPUS, and Cochrane databases.
  • Two-level bivariate meta-analysis using a random effects model.
  • Calculation of summary sensitivity, specificity, negative predictive value (NPV), and area under the hierarchical summary receiver-operating characteristic (HSROC) curve.

Main Results:

  • The area under the HSROC curve for NBI diagnosis was 0.92, indicating high diagnostic strength.
  • Overall sensitivity was 91.0% and specificity was 82.6% across 28 studies (6280 polyps).
  • High-confidence NBI predictions achieved 93.8% sensitivity and 83.3% specificity, with NPVs exceeding 90% in specific scenarios.

Conclusions:

  • NBI colonoscopy offers highly accurate real-time diagnosis of colorectal polyps, with an area under the HSROC curve >0.90.
  • High-confidence NBI predictions yield >90% sensitivity and NPV, supporting its potential for clinical use.
  • Endoscopic diagnosis using NBI demonstrated high agreement with pathology-based surveillance interval recommendations.