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Natural hypocholesterolemic agent: pectin plus ascorbic acid.

E Ginter, F J Kubec, J Vozár

    International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
    |January 1, 1979
    PubMed
    Summary

    Citrus pectin and ascorbic acid supplementation effectively reduced total cholesterol in both healthy individuals and hyperlipemic patients. This dietary intervention shows promise for managing high cholesterol levels.

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    Area of Science:

    • Nutritional Science
    • Biochemistry
    • Cardiovascular Health

    Background:

    • High cholesterol is a significant risk factor for cardiovascular disease.
    • Dietary interventions are crucial for managing hypercholesterolemia.
    • Citrus pectin and ascorbic acid are known for their potential health benefits.

    Purpose of the Study:

    • To investigate the effects of citrus pectin and ascorbic acid on cholesterol levels in humans.
    • To evaluate the efficacy of a pectin-ascorbic acid preparation in managing hypercholesterolemia.

    Main Methods:

    • A study involving guinea pigs demonstrated the cholesterol-lowering effects of citrus pectin and ascorbic acid in a high-fat diet.
    • Two human groups received a daily dose of 15 g pectin and 450 mg ascorbic acid for 6 weeks.

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  • Serum cholesterol and triglyceride levels were monitored in healthy individuals with mild hypercholesterolemia and hyperlipemic outpatients.

    • Main Results:

    • In healthy individuals, total serum cholesterol decreased by 8.6% (24 mg/100 ml).
    • In hyperlipemic outpatients, total serum cholesterol decreased by 18.7% (68 mg/100 ml).
    • High-density lipoprotein cholesterol levels remained unchanged, and changes in triglyceridemia were inconsistent.

    Conclusions:

    • Combined supplementation of citrus pectin and ascorbic acid can significantly reduce total serum cholesterol.
    • This dietary intervention is effective in both mildly hypercholesterolemic and hyperlipemic individuals.
    • Further research may be needed to explore the effects on triglyceridemia and long-term outcomes.