Related Experiment Video
Updated: May 15, 2026
Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
Published on: August 1, 2025
Prostate cancer with clear cell features and an unusual nested-like pattern of growth: a case report
Justine Varinot1, Sarah Drouin, Morgan Rouprêt
1Public Assistance Hospital of Paris, Department of Pathology, La Pitié-Salpetriere Hospital, University UPMC Paris VI, Paris, France. justinevarinot@hotmail.com
Background:
Clear cell carcinoma of the prostate is rare, with the majority of reports consisting of a single case study.
Case:
We report a case of prostate cancer with unusual cytoplasmic clearing and a nested-like pattern of growth observed in an 80-year-old patient with lower urinary tract obstruction. Emphasis is placed upon differential diagnosis and the distinction from other clear cell carcinomas arising in the urinary tract, both at a histological and immunohistochemical level.
Conclusion:
Androgen receptor immunohistochemistry seems to be a useful tool to distinguish prostate origin from secondary clear cell tumors.
