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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

[Current status and progress of fungal endophthalmitis treatment]

Shu-ran Wang1, Jun-jie Ye

  • 1Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|January 11, 2013
PubMed

Insights

Fungal endophthalmitis, an eye infection, is increasing due to antibiotic and steroid use. Treatment advances, including new antifungal drugs, offer improved outcomes for this serious condition.

Area of Science:

  • Ophthalmology
  • Mycology
  • Infectious Diseases

Context:

  • Fungal endophthalmitis incidence is rising, posing challenges for ophthalmologists.
  • Widespread use of broad-spectrum antibiotics and corticosteroids contributes to increased fungal infections.
  • Poor visual prognosis and risk of eyeball enucleation highlight the severity of this condition.

Purpose:

  • To review current treatment strategies for fungal endophthalmitis.
  • To highlight advancements in medications, surgical interventions, and etiological examination.
  • To emphasize the role of newer antifungal agents like voriconazole and liposomal amphotericin B.

Summary:

  • Fungal endophthalmitis is a severe intraocular infection with increasing incidence.
  • Treatment involves medications, surgery, and etiological diagnosis.
  • Emerging antifungal therapies, including voriconazole and liposomal amphotericin B, are crucial for management.

Impact:

  • Improved understanding of fungal endophthalmitis treatment options.
  • Enhanced clinical capacity for managing this challenging ophthalmic condition.
  • Potential for better visual prognoses through timely and appropriate interventions.

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