Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Obesity

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...

The Oral Microbiota

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

Development of the Oral Microbiota

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...

Drug Dosing: Obese Patients

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Investigating the Influence of Periodontal Disease on the Association Between Complex Multimorbidity and Health: A Cross-Sectional Study.

Journal of International Society of Preventive & Community Dentistry·2023

Same author

Identifying Factors Associated with Periodontal Disease Using Machine Learning.

Journal of International Society of Preventive & Community Dentistry·2023

Same author

Combinations of chronic conditions, functional limitations and geriatric syndromes associated with periodontal disease.

Family medicine and community health·2022

Same author

Presence of Specific Periodontal Pathogens in Prostate Gland Diagnosed With Chronic Inflammation and Adenocarcinoma.

Cureus·2021

Same author

Periodontal Manifestation of Type Ib Glycogen Storage Disease: A Rare Case Report.

Clinical advances in periodontics·2021

Same author

Papillon-Lefèvre or Haim-Munk Syndrome? Report on Two Sisters in a Consanguineous Family.

Clinical advances in periodontics·2020

Search research articles

Related Experiment Video

Updated: May 15, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Obesity and periodontitis: a link.

Charlene B Krejci¹, Nabil F Bissada

¹Department of Periodontics, Case Western Reserve University School of Dental Medicine, Cleveland, OH, USA.

General Dentistry

|January 11, 2013

Summary

Obesity and periodontitis are prevalent health issues linked by inflammation. This paper explores the inflammatory pathways connecting obesity and periodontitis, reviewing current literature on their association.

Area of Science:

Public Health
Immunology
Periodontology

Background:

Obesity affects one-third of the US population.
Periodontitis affects 50% of US adults over 30.
Both conditions are significant public health concerns.

Purpose of the Study:

To present the inflammatory pathways linking obesity and periodontitis.
To review existing literature on the association between these two conditions.

Main Methods:

Literature review of studies examining obesity and periodontitis.
Analysis of underlying inflammatory processes common to both diseases.

Main Results:

Inflammatory processes are a key link between obesity and periodontitis.

Related Experiment Videos

Last Updated: May 15, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Evidence suggests a significant association between the two conditions.

Conclusions:

Understanding the inflammatory link is crucial for public health strategies.
Further research into the obesity-periodontitis relationship is warranted.