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Long-term functional and quality-of-life outcomes after IPAA in children
Osnat Zmora1, Maya Natanson, Iris Dotan
1Department of Pediatric Surgery, Dana Children's Hospital, Tel-Aviv Sourasky Medical Center, affiliated with Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Diseases of the Colon and Rectum
|January 11, 2013
Summary
Outcomes after ileal pouch-anal anastomosis (IPAA) surgery in children show good functional results. However, parents perceive their child's quality of life more poorly than older patients, with no correlation to functional outcomes.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Quality of Life Research
Background:
- Ileal pouch-anal anastomosis (IPAA) demonstrates favorable long-term outcomes in adults.
- Limited data exist on functional outcomes and quality of life in pediatric patients following IPAA.
Purpose of the Study:
- To evaluate functional and quality-of-life outcomes in children after IPAA.
- To explore correlations between functional outcomes and quality of life in this pediatric cohort.
Main Methods:
- Utilized standardized, validated questionnaires for bowel/psychosocial functioning and quality of life assessment.
- Included pediatric patients (<18 years) followed at a tertiary medical center.
- Employed Global Assessment of Function Scale, Short Form 36, and Child Health Questionnaire-28 for outcome measurement.
Main Results:
- 26 pediatric patients (25 with ulcerative colitis) with a median 6-year follow-up were analyzed.
- Quality of life was comparable to the general population for older pediatric patients (>18 years at follow-up).
- Younger pediatric patients reported lower quality of life compared to the general population, with parental perception being poorer than patient self-perception and showing no correlation to functional results.
Conclusions:
- Pediatric patients undergoing IPAA achieve good functional outcomes.
- Parental perception of quality of life in younger pediatric patients is lower than patient self-perception and does not correlate with functional outcomes.
- The study's small sample size is a limitation.
