Related Experiment Video

Updated: May 15, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

Preoperative stroke and outcomes after coronary artery bypass graft surgery

Alex Bottle1, Abdul Mozid, Hilary P Grocott

  • 1School of Public Health, Imperial College London, UK.

Anesthesiology
|January 11, 2013
PubMed

Insights

Timing of coronary artery bypass grafting (CABG) after stroke did not affect mortality or length of stay. However, a longer interval slightly increased postoperative stroke risk, while combined stroke and myocardial infarction significantly raised perioperative risk.

Area of Science:

  • Cardiovascular Surgery
  • Neurology
  • Health Services Research

Background:

  • Optimal timing for coronary artery bypass grafting (CABG) after stroke is unknown.
  • Preoperative stroke is a significant risk factor for adverse outcomes in CABG patients.

Purpose of the Study:

  • To investigate preoperative predictors of adverse outcomes in CABG patients.
  • To determine the impact of the time interval between stroke and CABG on outcomes.

Main Methods:

  • Analysis of elective CABG admissions from the Hospital Episode Statistics database (April 2006-March 2010).
  • Logistic regression used to identify independent preoperative factors affecting length of stay, postoperative stroke, and mortality.
  • Results presented as adjusted odds ratios (OR).

Main Results:

  • Prior stroke increased mortality (OR 2.20), postoperative stroke (OR 1.99), and prolonged length of stay (OR 1.31).
  • Time interval between stroke and CABG did not impact mortality or length of stay.
  • A longer interval slightly increased postoperative stroke risk (OR per month 1.02).
  • Combined prior stroke and myocardial infarction significantly increased death risk (OR 5.50).
  • Liver disease (OR 20.8) and renal failure (OR 4.59) also prominently affected mortality.

Conclusions:

  • No evidence suggests that recent preoperative stroke increases the risk of postoperative stroke, death, or prolonged stay after CABG.
  • The combination of prior stroke and myocardial infarction substantially elevates perioperative risk in CABG patients.
Abstract

More Related Videos

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

Published on: September 15, 2023

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...