Related Experiment Video

Updated: May 15, 2026

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
10:34

Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage

Published on: August 30, 2020

Cause-specific mortality of 1-year survivors of subarachnoid hemorrhage

Miikka Korja1, Karri Silventoinen, Tiina Laatikainen

  • 1Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland. miikka.korja@hus.fi

Neurology
|January 11, 2013
PubMed

Insights

Patients surviving one year after subarachnoid hemorrhage (SAH) face increased long-term mortality, primarily from cerebrovascular events. Aggressive management of risk factors like smoking and high blood pressure is crucial for these survivors.

Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Subarachnoid hemorrhage (SAH) survivors face long-term health challenges.
  • Assessing mortality risk in SAH survivors is critical for guiding clinical practice.

Purpose of the Study:

  • To evaluate long-term, cause-specific mortality rates and risk ratios in individuals surviving one year post-SAH.
  • To identify key risk factors contributing to excess mortality in this population.

Main Methods:

  • A population-based prospective cohort study utilized data from the National FINRISK Study (1972-2007).
  • Included 64,349 participants, identifying 437 SAH cases and 233 one-year survivors with matched controls.
  • Follow-up extended to 2009 using the Finnish Causes of Death Register.

Main Results:

  • 37.8% of one-year SAH survivors died during follow-up (median 8.6 years).
  • SAH survivors exhibited a 1.96-fold increased hazard ratio for death compared to controls.
  • Cerebrovascular diseases were the primary cause of excess mortality, with smoking, high blood pressure, and high cholesterol as key modifiable risk factors.

Conclusions:

  • One-year SAH survivors experience significantly higher long-term mortality.
  • This excess mortality is predominantly driven by cerebrovascular events.
  • Intensified intervention strategies targeting cerebrovascular risk factors are strongly recommended for SAH survivors.
Abstract

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