Related Experiment Video
Updated: May 15, 2026
05:53
Biomimetic Replication of Root Surface Microstructure using Alteration of Soft Lithography
Published on: August 5, 2020
Efficacy of root surface biomodification in root coverage: a systematic review
Guilherme H C Oliveira1, Eduardo A G Muncinelli
1Periodontics Program, Division of Periodontics, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo (HRAC/USP), Bauru, São Paulo, Brazil.
Journal (Canadian Dental Association)
|January 12, 2013
Summary
Root surface biomodification (RSB) did not improve clinical outcomes for root coverage procedures. This review found no evidence supporting the use of RSB before periodontal surgery for root coverage.
Area of Science:
- Periodontology
- Regenerative Dentistry
Background:
- Root surface biomodification (RSB) is utilized in periodontal plastic surgery.
- Clinical efficacy of RSB for root coverage remains unclear due to varied agents and techniques.
Purpose of the Study:
- To evaluate the efficacy of root surface biomodification in achieving root coverage.
- To assess the impact of RSB on clinical outcomes in periodontal regenerative procedures.
Main Methods:
- Systematic review of MEDLINE and Cochrane databases, supplemented by manual searches.
- Inclusion criteria focused on studies reporting clinical attachment level, probing depth, and percentage root coverage.
- Analysis of 6 studies employing agents like citric acid, EDTA, and laser therapy with various surgical techniques.
Main Results:
- Six studies met the inclusion criteria for analysis.
- Commonly used RSB agents included citric acid, ethylenediaminetetraacetic acid, and laser therapy.
- Surgical techniques involved free gingival grafts, connective tissue grafts, and coronally advanced flaps.
Conclusions:
- Root surface biomodification demonstrated no additional benefit for evaluated clinical parameters.
- Current evidence does not support the routine use of RSB prior to root coverage procedures.
