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Related Experiment Video

Updated: May 15, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Endophthalmitis caused by Acinetobacter baumanni: a case series.

R Roy¹, P Panigrahi, J Malathi

¹Vitreo Retina Services, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India. rayrupak@gmail.com

Eye (London, England)

|January 12, 2013

Summary

Acinetobacter baumanni endophthalmitis is rare and has poor outcomes. Ciprofloxacin shows 100% sensitivity, making it a potential first-line treatment for this serious eye infection.

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Last Updated: May 15, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis

Published on: February 6, 2021

Quantification, Viability Assessment, and Visualization Strategies for Acinetobacter Biofilms

Quantification, Viability Assessment, and Visualization Strategies for Acinetobacter Biofilms

Published on: August 4, 2023

Area of Science:

Ophthalmology
Infectious Diseases
Microbiology

Background:

Endophthalmitis, a severe intraocular infection, can lead to vision loss.
Acinetobacter baumanni is an opportunistic pathogen increasingly recognized in healthcare-associated infections.

Observation:

This study analyzed four cases of Acinetobacter baumanni endophthalmitis in Eastern India (2009-2011).
Cases were predominantly post-cataract surgery or post-traumatic.
Acinetobacter baumanni was isolated from vitreous samples in all cases.

Findings:

All isolates were 100% sensitive to ciprofloxacin but resistant to ceftazidime.
Visual and anatomical outcomes were generally poor, with one patient achieving 20/200 vision.

Implications:

Acinetobacter baumanni is a rare but devastating cause of endophthalmitis.
Ciprofloxacin is a promising first-line intravitreal antibiotic for Acinetobacter baumanni endophthalmitis.
Early diagnosis and targeted antibiotic therapy are crucial for managing this condition.