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Updated: May 15, 2026

Synthesis and Characterization of Amphiphilic Gold Nanoparticles
Published on: July 2, 2019
Analysis of the formation process of gold nanoparticles by surface-assisted laser desorption/ionization mass
Iva Tomalová1, Chia-Hsin Lee, Wen-Tsen Chen
1CEITEC MU and Department of Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic.
Abstract:
Chemical reactions of reducing agents in the gold nanoparticle (AuNP) formation process were characterized using surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS). As the reaction of the AuNPs progresses, the produced AuNPs can serve as an efficient SALDI substrate. SALDI-MS revealed that the reducing agents and their oxidation products can be determined in the mass spectra. With respect to the transmission electron microscopic and UV-Vis spectroscopic examination of AuNPs, SALDI-MS results confirm not only the tendency toward AuNPs formation, but also reflect the information of the redox reaction process. Our results provide useful information for developing SALDI-MS methods to explore the chemical information regarding the surface behavior between adsorbates and nanomaterials.
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