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Related Concept Videos

Differentiation of Common Myeloid Progenitor Cells01:15

Differentiation of Common Myeloid Progenitor Cells

Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...

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Updated: May 15, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
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Multiple myeloma, version 1.2013.

Kenneth C Anderson1, Melissa Alsina, William Bensinger

  • 1Dana-Farber Cancer Institute/Brigham and Women's Cancer Center.

Journal of the National Comprehensive Cancer Network : JNCCN
|January 12, 2013
PubMed
Summary
This summary is machine-generated.

Newer treatment options and risk management strategies for relapsed or progressive multiple myeloma are detailed in the 2013 NCCN Guidelines. These updates focus on salvage therapy for patients with multiple myeloma.

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Area of Science:

  • Hematology
  • Oncology
  • Clinical Practice Guidelines

Background:

  • Multiple myeloma management requires updated strategies for relapsed or progressive disease.
  • The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment.

Purpose of the Study:

  • To summarize key updates in the 2013 NCCN Guidelines for Oncology concerning relapsed or progressive multiple myeloma.
  • To highlight new salvage therapy regimens and adverse event mitigation strategies.

Main Methods:

  • Review of the 2013 NCCN Clinical Practice Guidelines in Oncology for Multiple Myeloma.
  • Identification of changes related to relapsed or progressive disease management.

Main Results:

  • Addition of novel therapeutic regimens for salvage therapy in multiple myeloma.
  • Inclusion of strategies to manage side effects and risks of new treatments.

Conclusions:

  • The 2013 NCCN Guidelines offer updated approaches for managing relapsed/progressive multiple myeloma.
  • New salvage therapies and supportive care measures are emphasized for improved patient outcomes.