Unilateral corneal intraepithelial neoplasia: management of the recurrent lesion

Corneal intraepithelial neoplasia is an uncommon entity that may recur with potential for local invasive growth. Disease severity ranges from mild to severe dysplasia, the latter representing intraepithelial carcinoma in situ. Our case focuses on the importance of the neighboring bulbar conjunctiva in promoting recurrence of the corneal pathology. Over eight years, there were recurrences after debridement. After removal of grossly normal but histologically dysplastic bulbar conjunctival mucosa bordering the evident corneal process, successful control was achieved. There has been no recurrence for five years.