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Updated: May 15, 2026
Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
Fibrin clot extension on zirconia surface for dental implants: a quantitative in vitro study
Tonino Traini1, Sergio Caputi, Enrico Gherlone
1Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti-Pescara, Italy; Department of Dentistry, San Raffaele Hospital, Vita Salute University, Milano, Italy.
Purpose:
The surface chemical and physical properties of materials used for implants have a major influence on blood clot organization. This study aims to evaluate the blood clot extension (bce) on zirconia and titanium. bce was measured in association to surface roughness (Ra) and static contact angle (θ).
Materials And Methods:
Forty disk-shaped samples of sandblasted yttria tetragonal zirconia polycrystal (sb-YTZP), machined titanium (m-Ti), and sandblasted, high-temperature, acid-etched titanium (p-Ti) were used in the present study. About 0.2 mL of human blood, immediately dropped onto the specimen's surface and left in contact for 5 minutes at room temperature, was used to measure the bce. Specimens were observed under confocal scanning laser and scanning electron microscopes.
Results:
The bce (mean × 10(7) ± standard deviation [SD] × 10(6) μm(2) ) was 2.97 ± 6.68 for m-Ti, 5.64 ± 6.83 for p-Ti, and 3.61 ± 7.67 for sb-YTZP. p-Ti samples showed a significantly higher bce. Ra (mean ± SD [μm]) was 0.56 ± 0.7 for m-Ti, 3.78 ± 0.8 for p-Ti, and 2.68 ± 0.6 for sb-YTZP. The difference was not significant between sb-YTZP and p-Ti. θ (mean ± SD) was 55.6 ± 5.6 for m-Ti, 48.7 ± 2.8 for sb-YTZP, and 38.0 ± 2.2 for p-Ti. The difference was not significant between m-Ti and sb-YTZP.
Conclusions:
The sb-YTZP demonstrated a significantly lesser amount of bce compared with p-Ti specimens, notwithstanding that any significant difference was present between Ra and θ.
