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Related Concept Videos

Comparing Copy Number Variations and SNPs02:26

Comparing Copy Number Variations and SNPs

Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles, which...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Three Developmental Domains01:29

Three Developmental Domains

Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...

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Related Experiment Video

Updated: May 15, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
09:16

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants

Published on: February 21, 2015

Child development and structural variation in the human genome.

Ying Zhang1, Rajini Haraksingh, Fabian Grubert

  • 1Yale University.

Child Development
|January 15, 2013
PubMed
Summary
This summary is machine-generated.

Structural variations, large DNA changes in the human genome, are common and can significantly impact child development. Understanding these genomic variations is crucial for developmental research.

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Area of Science:

  • Genomics
  • Human Genetics
  • Developmental Biology

Background:

  • Structural variation involves large-scale DNA alterations (insertions, deletions, rearrangements) in the human genome.
  • These variations are more prevalent than previously understood.
  • The impact of structural variations on normal child development is largely unknown but potentially significant.

Purpose of the Study:

  • To review the phenomenon of structural variation in the human genome.
  • To describe advanced genomics technologies used to study structural variation.
  • To provide examples of structural variations affecting child development.

Main Methods:

  • Review of current scientific literature.
  • Analysis of novel genomics technologies.
  • Case study examples of structural variations and child development.

Main Results:

  • Structural variations are a common feature of the human genome.
  • New technologies are transforming the study of structural variations.
  • Specific examples illustrate the link between genomic structural variations and child development.

Conclusions:

  • Structural variations represent a significant area of human genomics research.
  • Further investigation is needed to fully understand the effects of structural variations on child development.