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Impedance cardiographic hemodynamic variables and hypertension in elderly Han residents

Zhao Xiajuan1, Ding Ding, Huang Yanyan

  • 1Department of Geriatrics, Huashan Hospital, Fudan University, Shanghai, China.

Upsala Journal of Medical Sciences
|January 15, 2013
PubMed

Insights

Elderly hypertension is linked to lower cardiac output and higher systemic vascular resistance. Impedance cardiography reveals hemodynamic changes in aging and hypertension, aiding in better management.

Area of Science:

  • Cardiovascular Physiology
  • Geriatric Medicine
  • Hypertension Research

Background:

  • Aging is associated with increased arterial stiffness and elevated systolic blood pressure.
  • Hypertension superimposed on aging further exacerbates these hemodynamic changes.

Purpose of the Study:

  • To investigate the relationship between systolic blood pressure and hemodynamic variables in elderly individuals.
  • To evaluate how normal aging and hypertension affect hemodynamic parameters using impedance cardiography.

Main Methods:

  • A total of 670 elderly Han residents (aged 60-93 years) were studied.
  • Impedance cardiography was used for non-invasive hemodynamic assessment.
  • Subjects were categorized into hypertensive and normotensive groups and further stratified by systolic blood pressure.

Main Results:

  • Hypertensive patients exhibited significantly lower cardiac output and cardiac index compared to normotensive individuals.
  • Stroke volume and stroke index were lower, while systemic vascular resistance and its index were higher in the hypertensive group.
  • Higher systolic blood pressure correlated with reduced cardiac output and increased systemic vascular resistance.

Conclusions:

  • Aging increases arterial stiffness and systemic vascular resistance, elevating systolic blood pressure.
  • Hypertension further amplifies these age-related hemodynamic alterations.
  • Impedance cardiography provides valuable insights into hemodynamic mechanisms for improved hypertension management in the elderly.
Abstract

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