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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Working memory and impulsivity predict marijuana-related problems among frequent users.

Anne M Day1, Jane Metrik, Nichea S Spillane

  • 1Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University, Providence, RI 02912, United States. anne_day@brown.edu

Drug and Alcohol Dependence
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Summary
This summary is machine-generated.

Marijuana users with lower working memory and higher impulsivity are more prone to developing problems. These cognitive factors, executive working memory and trait impulsivity, are independent risks for marijuana-related issues.

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Area of Science:

  • Neuroscience
  • Psychology
  • Substance Abuse Research

Background:

  • Marijuana is a widely used illicit substance.
  • Individual differences in vulnerability to marijuana-related problems exist.
  • Deficits in working memory and high trait impulsivity may increase risk.

Purpose of the Study:

  • To examine the associations of working memory and trait impulsivity with marijuana-related problems in frequent users.

Main Methods:

  • Utilized baseline data from 104 frequent marijuana users.
  • Assessed working memory using Trail Making Test B and short-term memory capacity.
  • Measured trait impulsivity and marijuana-related problems.

Main Results:

  • Lower working memory predicted more marijuana-related problems.
  • Higher trait impulsivity scores were independently associated with more problems.
  • Short-term memory capacity did not predict problems.

Conclusions:

  • Reduced executive cognitive ability increases susceptibility to marijuana-related problems.
  • Trait impulsivity and executive working memory are independent risk factors.
  • Findings highlight cognitive vulnerabilities in marijuana users.