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Updated: May 15, 2026

A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity
Published on: May 28, 2014
Neurogenic respiratory failure
1Liverpool Heart and Chest Hospital, Liverpool, UK. charles.hind@lhch.nhs.uk
Abstract:
It is uncommon for the lungs to be primarily involved in neurological conditions but severe respiratory problems can arise indirectly. These are usually the result of disorders of central ventilatory control, respiratory muscle weakness, or bulbar involvement. The effects of those disorders can be predicted by an understanding of the nervous control mechanisms and mechanical factors that determine effective ventilation. Awareness of these potential complications, and the increased availability of more advanced diagnostic and monitoring techniques in everyday clinical practice, has resulted in the introduction of specific treatments to try to reduce consequent morbidity and mortality.
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