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Updated: May 15, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Immunosuppression-mediated hepatitis B reactivation diagnosed following an investigation into suspected
N Floret1, J P Cervoni, F Sheppard
1Réseau Franc-Comtois de Lutte contre les Infections Nosocomiales, centre hospitalier universitaire, Besançon, France. n1floretbassissi@chu-besancon.fr
Abstract:
In August 2006, the regional unit for nosocomial infection control (ARLIN) was notified of a case of symptomatic acute hepatitis B (HBV) infection in an immunosuppressed 87-year-old patient who had received a blood transfusion five months previously. Immunosuppression for the treatment of a variety of conditions is increasing. Immunosuppressed patients should be investigated for previous HBV infection and given pre-emptive therapy where indicated. We report our experience investigating a case of HBV reactivation in an immunosuppressed patient. We describe the investigation and highlight the continued need for vigilance for HBV reactivation in immunosuppressed patients who may present to a range of clinicians.
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