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Updated: May 15, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Optimization of women's health before conception when pregnancy has been postponed
Joachim W Dudenhausen1, Amos Grunebaum, Ursula M Staudinger
1Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY, USA.
Objectives:
In the industrialized world, the mean age at which mothers give birth to their first child has increased. The purpose of this article was to review the available evidence in order to optimize preconception care in women who have postponed childbearing to the later years of the reproductive life cycle.
Methods:
Review of literature.
Results:
There is a paucity of evidence and rigorous studies to advise mothers on the potential interventions for optimizing pregnancy outcome.
Conclusions:
Evidence-based guidelines for advising women who postponed childbearing are scant, and further research in this important area is urgently needed.
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