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Updated: May 15, 2026

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
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The grape berry-specific basic helix-loop-helix transcription factor VvCEB1 affects cell size.

Philippe Nicolas1, David Lecourieux, Eric Gomès

  • 1Université de Bordeaux, INRA/ ISVV, Ecophysiologie et Génomique Fonctionnelle de la Vigne, Villenave d'Ornon, France.

Journal of Experimental Botany
|January 15, 2013
PubMed
Summary
This summary is machine-generated.

Researchers identified Vitis vinifera cell elongation bHLH protein (VvCEB1), a transcription factor crucial for grape berry development. VvCEB1 specifically promotes cell expansion during fruit growth, impacting auxin pathways.

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Area of Science:

  • Plant Biology
  • Molecular Genetics
  • Fruit Development

Background:

  • Grapevine berry development involves intricate physiological and biochemical processes.
  • Molecular mechanisms governing grapevine berry growth remain incompletely understood.
  • Fruit development progresses through distinct phases of cell division and expansion.

Purpose of the Study:

  • To identify and characterize a novel transcription factor regulating cell expansion in grapevine berries.
  • To elucidate the role of Vitis vinifera cell elongation bHLH protein (VvCEB1) in grape berry development.

Main Methods:

  • Identification and characterization of the VvCEB1 gene and its protein product.
  • Analysis of VvCEB1 expression patterns in grape berry tissues.
  • Promoter activity assays in tomato to confirm tissue-specific expression.
  • Overexpression studies in grape embryos to assess VvCEB1 function.

Main Results:

  • VvCEB1, a basic helix-loop-helix (bHLH) transcription factor, was identified and characterized.
  • VvCEB1 expression is specific to berry-expanding tissues, peaking around veraison.
  • VvCEB1 overexpression in grape embryos stimulated cell expansion.
  • VvCEB1 influences the expression of genes involved in cell expansion, including auxin metabolism and signaling pathways.

Conclusions:

  • VvCEB1 is a fruit-specific transcription factor that plays a key role in regulating cell expansion during grape berry development.
  • VvCEB1 acts by modulating the expression of genes critical for cell growth and hormonal regulation.
  • This study provides new insights into the molecular basis of grapevine fruit development.