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Published on: January 22, 2018
Current concepts on gastric carcinoid tumors
George C Nikou1, Theodoros P Angelopoulos
1Section of Gastrointestinal Neuroendocrinology, First Department of Propaedeutic Internal Medicine, Laiko Hospital, University of Athens Medical School, Agiou Thoma 17, Goudi, 11527 Athens, Greece.
Gastroenterology Research and Practice
|January 15, 2013
Summary
Gastric carcinoid tumors (GCs) are rare stomach neoplasms with three types. Treatment for GCs varies by type, size, and number, with surgical options for Type III and surveillance or endoscopic removal for Types I and II.
Area of Science:
- Gastroenterology
- Oncology
- Endocrinology
Background:
- Gastric carcinoid tumors (GCs) are rare, accounting for <1% of stomach neoplasms.
- Three distinct types of GCs exist, each with unique characteristics and associations.
- Type I (70-85%) links to chronic atrophic gastritis; Type II (5-10%) associates with Zollinger-Ellison syndrome and MEN1; Type III (15-25%) presents an aggressive course.
Purpose of the Study:
- To review the classification and current management strategies for gastric carcinoid tumors.
- To highlight the varying clinical approaches based on GC type, size, and quantity.
- To discuss emerging therapeutic options for gastric carcinoid tumors.
Main Methods:
- Literature review of gastric carcinoid tumor classifications.
- Analysis of treatment modalities for different GC types.
- Evaluation of emerging therapies such as somatostatin analogues.
Main Results:
- Gastric carcinoid tumors are categorized into three types with distinct clinical behaviors.
- Type III GCs universally warrant surgical treatment.
- Management for Type I and II GCs includes surveillance, endoscopic polypectomy, or surgical resection, with somatostatin analogues as a potential option.
Conclusions:
- Optimal management of gastric carcinoid tumors is type-dependent.
- A tailored approach considering tumor characteristics is crucial for effective treatment.
- Further research into novel therapies may improve outcomes for gastric carcinoid tumors.
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