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Updated: May 15, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
[Generalized pustular psoriasis of pregnancy]
Emily Avitan-Hersh1, Shay Erisson, Reuven Bergman
1Department of Dermatology, Rambam Health Care Campus, Haifa, Israel. edermatology@gmail.com
Pustular psoriasis of pregnancy is a rare entity. Clinically, it is characterized by an acute eruption of erythematous plaques studded with pustules during the third trimester. It may be localized or may spread to become generalized. The rash may be accompanied by constitutional symptoms and followed by complications such as sepsis, tetany secondary to hypocalcemia, placental insufficiency, and fetal morbidity and mortality. Therefore, early diagnosis and treatment are important. We present a case report of a patient who responded to corticosteroids and a review of the literature.
Pustular psoriasis of pregnancy is a rare entity. Clinically, it is characterized by an acute eruption of erythematous plaques studded with pustules during the third trimester. It may be localized or may spread to become generalized. The rash may be accompanied by constitutional symptoms and followed by complications such as sepsis, tetany secondary to hypocalcemia, placental insufficiency, and fetal morbidity and mortality. Therefore, early diagnosis and treatment are important. We present a case report of a patient who responded to corticosteroids and a review of the literature.
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