[Plasmapheresis--a therapeutic method for immunity-related infertility?]

In a 30-year-old woman with primary idiopathic sterility the immunological cause of infertility was assessed (spermagglutination antibodies in serum and in the ovulation mucus of the uterine cervix). The patient was treated without success by condom therapy, general and local immunosuppression. Therefore treatment by means of membrane separation plasmapheresis was started during two preovulation periods. Serum spermagglutination antibodies class IgM declined from the original titre of 1:1024 to 1:16, immediately after homologous inseminations they rose, however, to the original titre and the patient did not become pregnant.