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Related Experiment Video

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Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

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Published on: December 14, 2020

Baseline esophageal impedance according to different time intervals.

D Ummarino1, S Salvatore, B Hauser

  • 1UZ Brussel, Brussels, Belgium.

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
|January 16, 2013
PubMed
Summary

Calculating baseline impedance (BImp) to assess esophageal integrity is accurate when including impedance events (IEs). Automatic calculation of mean BImp over the entire recording, including IEs, is adequate for clinical use.

Keywords:
24-hour tracingbaseline esophageal impedancemonitoringmultichannel intraluminal impedancepHtime interval

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Area of Science:

  • Gastroenterology
  • Esophageal Physiology
  • Diagnostic Methods

Background:

  • Baseline impedance (BImp) is a key indicator of esophageal integrity.
  • Accurate BImp calculation is crucial for diagnosing esophageal conditions.
  • Current methods for BImp calculation may vary in efficiency and accuracy.

Purpose of the Study:

  • To determine the optimal method for calculating baseline impedance (BImp).
  • To compare BImp values obtained with and without impedance events (IEs).
  • To evaluate different time-based analysis methods for BImp calculation.

Main Methods:

  • 20 multichannel intraluminal impedance recordings were analyzed.
  • BImp was calculated including and excluding IEs (reflux, swallows, gas).
  • Short-term (1-minute) analysis periods were compared to full recording analysis.

Main Results:

  • The mean difference in BImp with and without IEs was minimal (≈1.2%).
  • Short-term analysis methods yielded BImp values comparable to full recording analysis.
  • Automatic calculation of mean BImp over the total tracing, including IEs, proved adequate.

Conclusions:

  • Automatic determination of mean BImp over the total tracing, including impedance events, is an adequate method.
  • For tracings with numerous IEs, 1-minute analysis every 4 hours is a viable alternative.
  • Software development is recommended for efficient BImp calculation excluding IEs.