Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 15, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

Novel prognostic scoring system after surgery for Klatskin tumor.

Gernot M Kaiser1, Andreas Paul, George Sgourakis

  • 1Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.

The American Surgeon
|January 16, 2013
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrated Psychosomatic Care in General Hospital Medicine: An Observational Study of Outcomes in Medically Complex Inpatients.

Journal of the Academy of Consultation-Liaison Psychiatry·2026
Same author

Proactive consultation-liaison-services (CL): comparing PHQ-4 screening with traditional referral pathways in medical inpatients - a prospective comparative pilot study.

BMC psychiatry·2026
Same author

Compound-Resolved VOC Dynamics in a Full-Scale Medium-Density Fibreboard Dryer: Process-State Screening Across Wood Furnish, Amino Resin Dosing, and Thermal Operating Variables.

Polymers·2026
Same author

Clinical and genomic profiling of <i>Klebsiella pneumoniae</i> in liver abscesses.

Virulence·2026
Same author

Cold Perfusion vs. Static Cold Storage of Deceased-Donor Kidneys - at 10 Years.

The New England journal of medicine·2025
Same author

Intraductal cryobiopsy via percutaneous cholangioscopy for biliary strictures: a multicenter feasibility study.

Endoscopy·2025

A new scoring system helps predict long-term outcomes for patients with Klatskin tumors (hilar cholangiocarcinoma). This system uses age, tumor stage, resection margin, and adjuvant therapy to guide treatment decisions.

Area of Science:

  • Hepatobiliary surgery
  • Surgical oncology
  • Gastroenterology

Background:

  • Klatskin tumor, a rare hilar cholangiocarcinoma, has poorly documented prognostic factors.
  • Accurate prediction of outcomes is crucial for patient management and treatment selection.

Purpose of the Study:

  • To identify significant prognostic factors for Klatskin tumor.
  • To develop and validate a predictive scoring system for long-term surgical outcomes.

Main Methods:

  • Prospective data collection from 96 patients undergoing resection for hilar cholangiocarcinoma (April 1998 - January 2007).
  • Evaluation of 31 potential prognostic variables using multivariate Cox proportional hazard regression.
  • Development of a scoring system based on age, pT status, R class (resection margin), and adjuvant chemoradiation.

More Related Videos

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Related Experiment Videos

Last Updated: May 15, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Main Results:

  • Age, pT status, R class, and adjuvant chemoradiation were significant prognostic factors.
  • A scoring system with three groups (score ≤6, score = 7, score = 8) showed statistical significance (P = 0.0332).
  • Median survival: 26.5 months (score ≤6), 12 months (score = 7), and 2.2 months (score = 8).

Conclusions:

  • A novel scoring system effectively predicts long-term survival in patients with Klatskin tumors.
  • This system can aid in selecting patients for further postoperative oncologic treatment.
  • Improved patient stratification may enhance treatment efficacy for hilar cholangiocarcinoma.