Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Outcome after a "perfect" Fontan operation.

F Fontan1, J W Kirklin, G Fernandez

  • 1Department of Cardiovascular Surgery, Hopital Cardiologique du Haut-Leveque, Bordeaux, France.

Circulation
|May 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of flow PRA on outcome in pediatric heart recipients in modern era: An analysis of the Pediatric Heart Transplant Study database.

Pediatric transplantation·2017
Same author

The Influence of Race and Common Genetic Variations on Outcomes After Pediatric Heart Transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2016
Same author

Recommendations for pathologic staging (pTNM) of cancer of the esophagus and esophagogastric junction for the 8th edition AJCC/UICC staging manuals.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2016
Same author

Worldwide Esophageal Cancer Collaboration: pathologic staging data.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2016
Same author

Worldwide Esophageal Cancer Collaboration: neoadjuvant pathologic staging data.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2016
Same author

Worldwide Esophageal Cancer Collaboration: clinical staging data.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2016
Same journal

Eugene Braunwald, MD, 1929-2026.

Circulation·2026
Same journal

AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026).

Circulation·2026
Same journal

Advancing Quality in the Evaluation, Surveillance, and Management of Aortic Stenosis: A Report From the AHA Target: AS Registry.

Circulation·2026
Same journal

Heart Failure Occurring in the Perinatal Period: A Scientific Statement From the American Heart Association.

Circulation·2026
Same journal

Correction to: 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Circulation·2026
Same journal

Correction to: The Natural History of Massive Left Ventricular Hypertrophy in Pediatric Hypertrophic Cardiomyopathy: A Multiregistry Analysis.

Circulation·2026
See all related articles

The Fontan operation, a palliative treatment for congenital heart disease, shows declining survival and functional capacity over time. The Fontan state itself, not surgical factors, appears responsible for these long-term outcomes.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • The Fontan operation is a surgical procedure for complex congenital heart disease.
  • Understanding long-term outcomes after the Fontan operation is crucial for patient management.

Purpose of the Study:

  • To determine early and long-term outcomes associated with the Fontan state.
  • To evaluate the impact of the transition to the Fontan state from congenital heart disease.

Main Methods:

  • Utilized a multivariate risk factor equation to predict survival rates.
  • Employed the theory of competing risks for survival and hazard function analysis.
  • Assessed patient functional capacity using the New York Heart Association (NYHA) class.

Related Experiment Videos

Main Results:

  • Predicted survival rates at 15 years post-Fontan operation were 73%.
  • A rapidly declining hazard phase at 6 months transitioned to a rising late hazard phase by 6 years.
  • Functional capacity (NYHA class) decreased with longer follow-up periods.
  • Older age at surgery was the only identified risk factor for late decline.

Conclusions:

  • The Fontan state per se contributes to premature decline in survival and function.
  • The late rise in hazard function is attributed to the Fontan state.
  • The Fontan operation is a palliative, not curative, procedure for congenital heart disease.