Should prophylactic antibiotics be used routinely in epistaxis patients with nasal packs?

T C Biggs1, K Nightingale, N N Patel

  • 1University Hospital Southampton NHS Foundation Trust, UK. tim_biggs@ymail.com.

Insights

Systemic antibiotics are often unnecessary for epistaxis (nosebleed) patients with nasal packing. A new algorithm reduced their use by 58.2% without increasing infection or rebleeding risks.

Area of Science:

  • Otolaryngology
  • Infectious Disease

Background:

  • Current practices for prophylactic antibiotic use in epistaxis patients with nasal packing are inconsistent.
  • Lack of validated guidelines contributes to variable treatment approaches.

Purpose of the Study:

  • To evaluate a new treatment algorithm aimed at reducing systemic antibiotic use in epistaxis patients.
  • To compare outcomes before and after implementing guidelines emphasizing topical antibiotics.

Main Methods:

  • A study involving 57 patients undergoing nasal packing for spontaneous epistaxis.
  • Implementation of new guidelines and a subsequent reaudit.
  • Telephone surveys at six weeks post-discharge to assess infective symptoms, rebleeding, and readmission.

Main Results:

  • Systemic antibiotic prescribing decreased by 58.2% after guideline implementation.
  • No statistically significant increase in infective nasal symptoms, rebleeding, or readmission rates was observed.
  • The audit validated the effectiveness of the new treatment algorithm.

Conclusions:

  • Systemic prophylactic antibiotics are generally not required for epistaxis patients with nasal packs.
  • Topical antibiotics may be a more appropriate, cost-effective, and equally effective alternative.
  • The new algorithm standardizes antibiotic use, potentially reducing healthcare costs.
Abstract

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