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Related Concept Videos

Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function. They...
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.

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Related Experiment Video

Updated: May 15, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Does cognitive remediation for schizophrenia improve functional outcomes?

Alice Medalia1, Alice M Saperstein

  • 1Columbia University College of Physicians and Surgeons, Department of Psychiatry, New York, New York, USA. Am2938@columbia.edu

Current Opinion in Psychiatry
|January 16, 2013
PubMed
Summary

Cognitive remediation for schizophrenia improves functional outcomes when integrated with real-world practice and psychosocial rehabilitation. Programs incorporating strategy teaching and addressing motivation yield better results.

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A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
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A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

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Last Updated: May 15, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills
07:31

A Computerized Functional Skills Assessment and Training Program Targeting Technology Based Everyday Functional Skills

Published on: February 13, 2020

Area of Science:

  • Psychiatry
  • Neuroscience
  • Rehabilitation Medicine

Background:

  • Cognitive deficits significantly impact functional outcomes in schizophrenia.
  • Cognitive remediation aims to improve cognition and functional outcomes in schizophrenia.
  • Previous research shows variable effects of cognitive remediation on functional outcomes.

Purpose of the Study:

  • To review recent literature on cognitive remediation for schizophrenia, focusing on psychosocial outcomes.
  • To identify factors influencing the effectiveness of cognitive remediation for functional improvement.
  • To synthesize findings on integrating cognitive remediation with other rehabilitation approaches.

Main Methods:

  • Systematic review of studies published since 2011.
  • Analysis of cognitive remediation programs targeting neurocognition, social cognition, or integrative skills.
  • Evaluation of impact on psychosocial outcomes including quality of life, employment, academic, and social functioning.

Main Results:

  • Cognitive remediation impacts cognition across various trial qualities.
  • Psychosocial outcomes are more variable but show promise.
  • Integrative approaches targeting a range of cognitive skills are increasingly common.

Conclusions:

  • Cognitive remediation is most effective for functional outcomes when skills are practiced in real-world settings.
  • Integrating cognitive remediation with psychosocial rehabilitation enhances functional outcomes.
  • Programs emphasizing strategy teaching, motivation, and belief modification outperform drill-and-practice methods.