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Updated: May 15, 2026

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
Published on: May 3, 2019
Novel monoisotopic 109AgNPET for laser desorption/ionization mass spectrometry
Joanna Nizioł1, Wojciech Rode, Barbara Laskowska
1Bioorganic Chemistry Laboratory, Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańców Warszawy Avenue, 35-959 Rzeszów, Poland.
Abstract:
Preparation is described of the surface of the first monoisotopic cationic (109)Ag nanoparticles (AgNPs), covering commercial and modified MALDI targets, along with examples of the use in MS analyses of various low-molecular-weight (LMW) organic compounds, including alkaloids, saccharides, amino acids, nucleosides, nucleic bases, and other organics. The new targets, compared to those covered by naturally occurring silver, allow analyte detection with higher sensitivity, mass accuracy, and resolution. Moreover, monoisotopic triatomic silver cations (109)Ag(3)(+) appear to be applicable for analyte cationization.
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