Related Experiment Videos
Complete nucleotide sequence of the sr gene from Streptococcus mutans OMZ 175
J A Ogier1, M Scholler, Y Leproivre
1Unité INSERM U 157 Faculté de Chirurgie Dentaire, Strasbourg, France.
FEMS Microbiology Letters
|March 1, 1990
Abstract:
The nucleotide sequence encoding the SR protein of Streptococcus mutans OMZ 175 (serotype f) has been determined. The sr gene consists of 4667 bp and codes for a 171177 Da protein. Comparison of the inferred amino acid sequence with the one of PAc antigen from S. mutans MT 8148 (serotype c) indicates a 88% conservation of amino acid residues which reflects the close relatedness of both proteins. Major differences in amino acid composition are located at the C-terminal part of the sequence where only 298 amino acids of the terminal 420 are conserved.