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Clinical features of inpatients with methamphetamine-induced psychosis

Bahareh Fasihpour1, Siamak Molavi, Seyed Vahid Shariat

  • 1Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Journal of Mental Health (Abingdon, England)
|January 18, 2013
PubMed
Abstract

Insights

Methamphetamine-induced psychosis (MIP) is rising in Iran, overwhelming psychiatric services. This study details the clinical features of 111 MIP inpatients, finding persecutory delusions and auditory hallucinations most common.

Area of Science:

  • Psychiatry
  • Toxicology
  • Epidemiology

Background:

  • Recent years have seen a surge in methamphetamine use in Iran.
  • This has led to an overload of psychiatric emergency services with cases of methamphetamine-induced psychosis (MIP).

Purpose of the Study:

  • To characterize the clinical presentation of inpatients diagnosed with methamphetamine-induced psychosis (MIP).
  • To analyze demographic and clinical data of MIP patients in a psychiatric hospital setting.

Main Methods:

  • Retrospective analysis of medical records for 111 MIP patients admitted to Iran Psychiatric Hospital between April 2008 and April 2010.
  • Data collected included details of the psychotic episode, substance use history, prior psychiatric conditions, and demographics.
  • Descriptive statistical methods were employed for data analysis.

Main Results:

  • The most frequent psychotic symptoms observed were persecutory delusion (82%) and auditory hallucination (70.3%).
  • Other common symptoms included reference delusion (57.7%), visual hallucination (44.1%), grandiosity delusion (39.6%), and jealousy delusion (26.1%).
  • The average duration of hospital admission was 21.43 days, with the psychotic episode lasting an average of 17.37 days; 8.75% of cases experienced symptoms exceeding one month.

Conclusions:

  • The prevalence of psychotic symptoms in this Iranian cohort aligns with previous international studies.
  • However, specific clinical aspects, such as the time from initial methamphetamine use to psychosis onset and the psychosis course, resemble earlier epidemics (e.g., Japan) more than recent ones.
  • This suggests that the relatively short history of methamphetamine use in Iran may influence the clinical presentation of MIP.

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