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Updated: May 15, 2026

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

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Published on: August 14, 2019

Relationship between endothelial dysfunction and nocturia with benign prostatic hyperplasia.

Mehmet Inci¹, Bahadir Sarli, Mursel Davarci

¹Department of Urology, Mustafa Kemal University School of Medicine, Hatay, Turkey.

Scandinavian Journal of Urology

|January 18, 2013

Summary

This summary is machine-generated.

Nocturia, or nighttime urination, is linked to endothelial dysfunction in men with benign prostatic hyperplasia (BPH). This finding suggests nocturia may be an early cardiovascular disease risk factor.

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Published on: June 16, 2014

Area of Science:

Urology
Cardiovascular Health
Endocrinology

Background:

Limited data exist on the relationship between nocturia, benign prostatic hyperplasia (BPH), and endothelial dysfunction.
Endothelial dysfunction is a precursor to cardiovascular disease.

Purpose of the Study:

To investigate the association between nocturia and endothelial dysfunction in patients diagnosed with BPH.

Main Methods:

Forty-two men with BPH and 42 age-matched controls were enrolled.
Assessments included nocturia frequency/duration, prostate volume, International Prostate Symptom Score (IPSS), and brachial flow-mediated dilatation (FMD).

Main Results:

A significant negative correlation was observed between FMD and both nocturia frequency (r = -0.879) and duration (r = -0.890).
FMD was significantly lower in the BPH group (6.0 ± 0.09%) compared to controls (7.8 ± 0.10%).

Conclusions:

Nocturia in BPH patients is associated with endothelial dysfunction.
Nocturia may serve as an unrecognized risk factor for cardiovascular disease in men with BPH.