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Updated: May 15, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
Published on: March 26, 2018
[High-risk patients with aortic valve stenosis. Interventional therapy]
R Bekeredjian1, S T Pleger, E Chorianopoulos
1Abteilung Innere Medizin III-Kardiologie, Angiologie und Pneumologie, Medizinische Universitätsklinik Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany. raffi.bekeredjian@med.uni-heidelberg.de
Transcatheter aortic valve implantation (TAVI) offers similar outcomes to surgery for high-risk patients with severe aortic stenosis. This approach expands treatment options for those unsuitable for traditional valve replacement surgery.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Context:
- Aortic valve stenosis is a common and serious heart valve disease in adults.
- Surgical valve replacement is standard but not suitable for all patients due to age and comorbidities.
- Transcatheter aortic valve implantation (TAVI) emerged as an alternative, particularly for high-risk individuals.
Purpose:
- To compare the efficacy and safety of TAVI versus surgical valve replacement in high-risk patients with severe aortic stenosis.
- To evaluate mortality rates and symptom reduction over a 2-year follow-up period.
Summary:
- The first randomized study demonstrated comparable 2-year mortality between TAVI and surgical valve replacement in operable high-risk patients.
- Both TAVI and surgical valve replacement led to similar reductions in symptoms.
- These findings support TAVI as a viable treatment option for severe aortic stenosis in high-risk populations.
Impact:
- TAVI expands therapeutic options for patients with severe aortic stenosis who are poor surgical candidates.
- The study provides evidence supporting the use of TAVI in specific high-risk patient groups.
- This research influences clinical decision-making for aortic stenosis management.
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