Serum immunoglobulins and complement in patients suffering from amoebic liver abscess

Immunoglobulins IgG, IgM & IgA and complement C3 were studied in 24 patients suffering from amoebic liver abscesses (ALA) before and two months after therapy. The results were compared with those of 12 healthy controls. IgG and IgA showed significant higher level in ALA patients than the normal controls, P less than 0.001 and P less than 0.01 respectively. IgM level was also higher than the normal controls but the difference was insignificant. Follow up of these Igs showed marked drop two months after therapy. C3 level was found statistically higher in ALA before therapy than that of the normal controls and that of patients two months after therapy. Correlation between C3 level and the size of the abscess showed that its level was statistically higher in large abscesses P less than 0.05.