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Updated: May 15, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Hyperkalemic recurrent bilateral lower extremity weakness in a patient on hemodialysis
Getaw Worku Hassen1, Suzanne Newstead, Lorraine Maria Giordano
1Department of Emergency Medicine, Metropolitan Hospital Center, NYMC, 1901 First Avenue, New York, NY 10029, USA.
Abstract:
Hyperkalemia is a severe life-threatening electrolyte disorder that commonly affects the cardiac conductivity and contractility. Ascending paralysis affecting the extremities with focal neurological deficit as well as quadriparesis and a seizure associated with hyperkalemia has been reported in the literature. Here, we describe a case of isolated recurrent lower extremity paralysis and an episode of seizure in an 83-year-old patient with end-stage renal disease on hemodialysis.
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Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
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