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Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
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Published on: February 2, 2024

[A man with persisting dyspnea].

Lizza E L Hendriks1, Michiel H M Gronenschild, Eric H J van Haren

  • 1Atrium Medisch Centrum, afd. Longziekten, Heerlen, the Netherlands. lizzahendriks@yahoo.com

Nederlands Tijdschrift Voor Geneeskunde
|January 19, 2013
PubMed
Summary
This summary is machine-generated.

A 67-year-old male developed metastatic pulmonary artery sarcoma, initially presenting as a pulmonary embolism. Advanced imaging revealed tumor spread to the pleura and bones, confirmed by biopsy.

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Pulmonary embolism (PE) is a common condition often treated with anticoagulation.
  • Recurrent or worsening PE can indicate underlying malignancy or treatment failure.

Observation:

  • A patient with a history of PE presented with worsening symptoms and new thoracic abnormalities on CT.
  • 18FDG-PET-CT demonstrated increased metabolic activity in pleural nodules, fluid, and bone lesions.

Findings:

  • Bone biopsy confirmed leiomyosarcoma, establishing the diagnosis of metastatic pulmonary artery sarcoma.
  • The findings indicate a rare presentation of sarcoma metastasizing to the pulmonary artery and spreading to the pleura and skeleton.

Implications:

  • This case highlights the importance of considering malignancy in patients with atypical or progressive PE.
  • Advanced imaging like PET-CT is crucial for staging and diagnosing rare sarcomas.
  • Metastatic pulmonary artery sarcoma requires a multidisciplinary approach for management.