Renal transplantation in Mississippi

Area of Science:

• Nephrology
• Transplantation Surgery
• Immunosuppression

Background:

• Review of cadaveric renal transplantation and organ donation in Mississippi (1984-1988).
• Cyclosporine introduction has improved patient and graft survival rates.
• Significant disparity noted between state and national rates of end-stage renal disease (ESRD) patient transplantation.

Purpose of the Study:

• To review and analyze the outcomes of cadaveric renal transplantation in Mississippi.
• To assess the impact of cyclosporine on transplant success.
• To compare transplantation rates in Mississippi with national averages.

Main Methods:

• Retrospective review of cadaveric renal transplant data from Mississippi.
• Analysis of patient and graft survival rates.
• Comparison of annual transplantation rates for end-stage renal disease (ESRD) patients.

Main Results:

• Primary cadaveric renal transplants in Mississippi show 93% patient survival and 82.3% graft survival.
• Continuous improvement in outcomes attributed to cyclosporine use.
• Only slightly over 1% of Mississippi ESRD patients receive transplants annually, versus 7.5% nationally.

Conclusions:

• Cadaveric renal transplantation outcomes in Mississippi have improved significantly.
• Cyclosporine is a key factor in enhancing transplant success.
• There is a substantial underutilization of renal transplantation for ESRD patients in Mississippi compared to national trends.