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Updated: May 15, 2026
08:18
Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
Published on: February 8, 2022
Predictors for recurrent primary intracerebral hemorrhage: a retrospective population-based study
Juha Huhtakangas1, Pekka Löppönen, Sami Tetri
1Department of Neurology, Oulu University Hospital, Oulu, Finland. juha.huhtakangas@ppshp.fi
Stroke
|January 19, 2013
Summary
A prior ischemic stroke significantly increases the risk of recurrent primary intracerebral hemorrhage (PICH). This finding highlights the importance of considering stroke history when managing PICH patients.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Primary intracerebral hemorrhage (PICH) recurrence is a significant concern.
- Comorbidities, prior strokes, and medications may influence PICH risk.
Purpose of the Study:
- To identify independent predictors of recurrent PICH.
- To analyze factors associated with PICH recurrence in a defined population.
Main Methods:
- Retrospective cohort study of 961 patients with first-ever PICH.
- Utilized hospital records, death records, and national prescription data.
- Employed Kaplan-Meier curves and Cox proportional hazards models.
Main Results:
- 58 patients experienced 68 recurrent PICH events over 3481 person-years.
- Univariable analysis showed history of ischemic stroke, diabetes, and aspirin use were associated with higher recurrence.
- Multivariable analysis confirmed previous ischemic stroke as an independent predictor (aHR 2.22).
Conclusions:
- Previous ischemic stroke is an independent risk factor for PICH recurrence.
- Diabetes mellitus showed a trend towards increased risk, while treated hypertension trended towards decreased risk of fatal recurrence.
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